The Weight Loss Benefit of Green Tea

For 4,000 years, Asians have regarded green tea as something more than just a beverage. Green tea was used as herbal medicine and treatment for everything from headaches to depressions and even to wei...

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Ayurvedic Medicine, Remedies and Treatment
Explores Ayurvedic medicine, including home remedies and herbs for specific conditions. Ayurvedic methods treat both the ailment and the whole person, emphasizing the prevention of disease to avoid the need for a cure.
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What Are The Risk Factor Of Breast Cancer

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You might wonder why someone would actually introduce bacteria into their diet. Bacteria are inhabiting in your body right now, over 3 pounds of it just in your intestines. That by all odds makes you ... Prevent or Reverse Heart Disease William Walters http://Heart-Condition-Guide.com/ Friday, 1:07 pm Today we are going to talk about different types of Heart Dis... A Different Type of Office Furniture - The Kneeling Stool Given the amount of time most of us spend sitting at computer desks in our jobs and at home, it is not surprising that we put a lot of stress on our lower backs. Sitting in a office chair for 8 - 10 ... The Costs Of LASIK Eye Surgery? LASIK eye surgery is generally considered to be more expensive than other more conventional surgical procedures. This can in part be attributed to the use of high-tech equipment such as lasers. Havi... [Author: L Jimmy Roos - Health - August 25, 2006] Key features that you should be looking for in ergonomic seating Today our economy has been described as knowledge based which is why many of us work at a computer desk and are familiar with ergonomics. A large percentage of the workforce spends most of their time... Diabetes: Prevention is the Best Cure There are 800,000 new diabetes cases diagnosed annually in the United States, and this number is expected to rise. Diabetes is a chronic disease that claims many lives each year. It is the number six ... Athletes Foot Cures That Work With the beating our feet take on a daily basis it's a wonder there is any athletes foot cures that work. Think about it for a minute. Our feet are stood on for countless hours each day under our bodi... Cholesterol Diet & Heart Attack William Walters http://Lowering-Cholesterol-Facts.com/ Friday, 9:45 pm Today we are going to talk about the importance of Lowe...

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Fat Burning Cardio Workouts with Heart Rate Monitors

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Aleve, Vioxx, Celebrex And Bextra: What You Need To Know About Arthritis Pain Medications

Recent controversy about the safety of pain medications for arthritis has left patients and health care professionals alike confused about which medications are safe to use. In fact, a recent survey by the Boston-based Rippe Lifestyle Institute indicated that many people with arthritis are suffering unnecessarily because they have stopped or reduced their use of pain relievers due to confusion about which drugs are considered safe.

The survey also showed that now, more than ever, those with arthritis need to understand the benefits and possible side effects associated with all arthritis pain medications. In order to do so, people with arthritis, their caregivers and families must be familiar with recent news about the two types of drugs most commonly used to treat arthritis pain – non-selective, non-steroidal anti-inflammatory drugs (NSAIDs), and another group of NSAIDs known as cyclooxygenase-2 (COX-2) specific inhibitors.

COX-2 specific inhibitors vs. Other NSAIDs

COX-2 specific inhibitors are the newest members of the NSAID class of medications. Available by prescription only, they became widely used in recent years to reduce joint pain and swelling. COX-2 specific inhibitors work by selectively blocking, or inhibiting, one of the two enzymes associated with inflammation. Some experts think that this selective inhibition may be one reason for some of the negative side effects currently associated with COX-2 specific inhibitors.

Non-selective NSAIDs were developed earlier than COX-2 specific inhibitors and have been widely used to relieve arthritis pain and inflammation for many years. Unlike COX-2 specific inhibitors, non-selective NSAIDs inhibit both major enzymes involved in the inflammatory process, COX-1 and COX-2. The non-selective NSAID category includes a number of different medications that are available in both prescription and over-the-counter (OTC) products.

Timeline of Events

To understand the current state of affairs, it is important to understand the sequence of events. The controversy started when a study published in the October 21, 2004, issue of the New England Journal of Medicine cited the COX-2 specific inhibitor, Vioxx as potentially causing “major adverse events,” including heart attack and stroke, among patients taking the drug. As a result, Merck (the drug’s manufacturer) voluntarily withdrew Vioxx from the market. However, in the months following, the safety of the other available COX-2 specific inhibitors such as Celebrex and Bextra, as well as other arthritis pain medications in the non-steroidal anti-inflammatory (NSAID) class, were also called into question.

Consequently, in February 2005, the US Food and Drug Administration (FDA) convened a special Advisory Committee, made up of members of the Arthritis and Drug Safety Advisory Committees, to review the cardiovascular safety of these arthritis pain medications.

FDA Directive: Stronger Warning Labels for Some Pain Medications

On April 7, 2005, taking into account the recommendations of the Advisory Committee, the FDA issued the following directives:

• Bextra, a COX-2 specific inhibitor manufactured by Pfizer, was withdrawn from the market.

• All prescription NSAIDs must revise their labeling to include a “black box” warning that highlights the potential increased risk for cardiovascular (CV) events as well as the potentially life threatening gastrointestinal (GI) bleeding associated with these drugs. Celebrex, the only COX-2 specific inhibitor remaining on the US market, was included in this directive.

• All OTC NSAIDs (except aspirin) will be required to revise their labeling to include more specific information about the potential for GI and CV side effects, a stronger reminder to follow label instructions, as well as a warning about potential skin reactions.

To further evaluate the potential for increased CV risk, the FDA also announced that all NSAIDs must conduct and submit to the FDA a comprehensive review and analysis of pertinent safety data from clinical trials.

• Aleve (naproxen sodium) is supported by clinical studies conducted to gain approval of naproxen as a prescription product and as OTC that do not provide any evidence of increased risk of cardiovascular events.

Treatment Options: What Should Arthritis Patients Know?

For some people who suffer from pain associated with arthritis, their symptoms can be managed with exercise, heat/cold therapy, joint protection, assistive devices, weight control, or in some severe cases, surgery. For others, medications are needed to help manage the symptoms associated with arthritis.

When taken as directed OTC medications such as Aleve provide a safe and effective way to treat mild to moderate pain of minor arthritis. If patients have questions, they should consult their health care professional about which treatment option is most appropriate.

Why It’s Important to Treat Arthritis

Arthritis affects approximately 66 million Americans and is the nation’s leading cause of disability. There are over 100 different types of arthritis, and they all have different symptoms that vary in severity from person to person. The most common form of arthritis, osteoarthritis, is characterized by the breakdown of cartilage that causes the bones to rub together, resulting in pain, loss of movements and stiffness . Arthritis is usually a chronic condition.

For more information on Aleve and naproxen, visit the Aleve website at www.aleve.com
For more information on arthritis pain relief, visit www.arthritis.org
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